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NDC

National Drug Code

The NDC is the FDA identifier for a specific drug product at the package level — identifying manufacturer, product, and package size for dispensing and billing.

The National Drug Code (NDC) is the FDA's unique identifier for drug products in the United States. Each NDC encodes a labeler (manufacturer), a specific product (strength, dosage form, formulation), and a package size — the granularity needed for dispensing, inventory, and claims.

Because NDC is package- and manufacturer-specific, it is more granular than RxNorm's clinical-drug concept. A single RxNorm concept can correspond to many NDCs. Crosswalking between them is a routine but error-prone task that terminology services exist to handle.

NDC appears throughout pharmacy claims (NCPDP Telecom, X12 837), dispensing records, and the drug supply chain, making accurate NDC handling essential for the pharmacy interoperability surface.

How this relates to Health1st

Health1st normalizes and crosswalks NDC ↔ RxNorm at the dispensing granularity pharmacy claims require — for example resolving a product like ATORVASTATIN CALCIUM, NDC 59651-608, to its clinical-drug concept and back.

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